Postdoc in Cancer Immunology

Postdoc in Cancer Immunology

Employer

Dana-Farber Cancer Institute

Location

Boston, Massachusetts

Salary

Competitive postdoctoral salary

Closing date

Sep 7, 2026

Discipline

Life Sciences, Immunology

Position Type

Full Time

Job Type

Postdoc

Organization Type

Academia

Job Details

A postdoctoral position is available in Kai Wucherpfennig’s lab at Dana-Farber Cancer Institute.  The project focuses on the development of novel cancer immunotherapy strategies based on discovery of major resistance pathways.  We are particularly interested in therapeutic strategies that induce a cooperative response by multiple immune cell populations, including dendritic cells, T cells and NK cells.

An example is our discovery of the epigenetic enzyme CARM1 as an immunotherapy target because it is relevant in all major cell populations of the cancer – immunity cycles, specifically dendritic cells, T cells and cancer cells.  CARM1 represents the first small molecule target for enhancing dendritic cell function in tumors, and inhibition of this enzyme sensitizes PD-1 resistant cancers resistant to immune attack (Science July 2026).

Our research integrates investigation of tumor immunity in clinical specimens with in-depth mechanistic analyses in relevant mouse models.  We are currently investigating the organization of immune responses in human cancers using high-dimensional spatial transcriptomics and proteomics technologies (Cell March 2026).

The lab and our department offer a vibrant and stimulating environment for research in immunology, and we have ongoing collaborations with outstanding basic, translational and clinical investigators.  To learn more about our lab, visit our website: https://labs.dana-farber.org/t-cells-treating-cancer/